{
  "_id": "6aaa8b7eea78b3e62eacdd59",
  "Package": "IntegMultiReg",
  "Title": "Integrative Bayesian Multiple Regression for Multi-Platform\nBiomarkers",
  "Version": "0.1.3",
  "Authors@R": "c(\nperson(\"Sinian\", \"Zhang\", email = \"zhan9381@umn.edu\",\nrole = \"aut\"),\nperson(\"Jianfeng\", \"Wang\", email = \"wan01188@umn.edu\",\nrole = \"aut\"),\nperson(\"Thierry\", \"Chekouo\", email = \"tchekouo@umn.edu\",\nrole = c(\"aut\", \"cre\"),\ncomment = c(ORCID = \"0000-0002-3594-9182\")))",
  "Description": "A Bayesian framework that integrates several regression\nmodels to identify a parsimonious set of biomarkers shared\nacross disparate data platforms (for example genomic,\ntranscriptomic and proteomic assays). Subjects are partitioned\ninto subgroups defined by their pattern of platform\navailability, so that no subject with partially missing\nplatform data is excluded, and information is borrowed across\nsubgroups through a Markov random field prior on the\nvariable-selection indicators together with non-local (product\nmoment) priors on the regression effects. The methodology was\nintroduced for time-to-event outcomes by Chekouo, Stingo,\nDoecke and Do (2017) <doi:10.1111/biom.12587>; this package\nadditionally supports continuous (Gaussian) and binary (probit)\noutcomes. Posterior inference is carried out by a Markov chain\nMonte Carlo sampler implemented in C for computational\nefficiency.",
  "License": "GPL (>= 3)",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "SystemRequirements": "GSL (>= 2.0)",
  "VignetteBuilder": "knitr",
  "Config/testthat/edition": "3",
  "NeedsCompilation": "yes",
  "Config/roxygen2/version": "8.0.0",
  "RoxygenNote": "7.3.2",
  "Packaged": {
    "Date": "2026-09-16 12:20:22 UTC",
    "User": "root"
  },
  "Author": "Sinian Zhang [aut], Jianfeng Wang [aut], Thierry Chekouo [aut,\ncre] (ORCID: <https://orcid.org/0000-0002-3594-9182>)",
  "Maintainer": "Thierry Chekouo <tchekouo@umn.edu>",
  "Config/pak/sysreqs": "libgsl0-dev",
  "Repository": "https://chekouo.r-universe.dev",
  "Date/Publication": "2026-09-16 11:49:46 UTC",
  "RemoteUrl": "https://github.com/cran/IntegMultiReg",
  "RemoteRef": "HEAD",
  "RemoteSha": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
  "_user": "chekouo",
  "_type": "src",
  "_file": "IntegMultiReg_0.1.3.tar.gz",
  "_fileid": "https://r2.ropensci.org/adebad36b6542bf0ed832a598b9031ac204d5bddb7216275e41c36fd9074144a",
  "_filesize": 801978,
  "_sha256": "adebad36b6542bf0ed832a598b9031ac204d5bddb7216275e41c36fd9074144a",
  "_expires": "2026-12-25T12:28:44.000Z",
  "_created": "2026-09-16T12:20:22.000Z",
  "_published": "2026-09-16T12:28:46.423Z",
  "_jobs": [
    {
      "job": 104790967362,
      "time": 152,
      "config": "linux-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "10445908298"
    },
    {
      "job": 104790967255,
      "time": 191,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "10445034341"
    },
    {
      "job": 104790967270,
      "time": 127,
      "config": "linux-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10446210928"
    },
    {
      "job": 104790967246,
      "time": 116,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10446131422"
    },
    {
      "job": 104790967280,
      "time": 246,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "10445932435"
    },
    {
      "job": 104790967225,
      "time": 280,
      "config": "macos-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "10446195879"
    },
    {
      "job": 104790967226,
      "time": 224,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10445913810"
    },
    {
      "job": 104790967278,
      "time": 298,
      "config": "macos-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10446445884"
    },
    {
      "job": 104789782987,
      "time": 223,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10445424559"
    },
    {
      "job": 104790967133,
      "time": 110,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "10445243689"
    },
    {
      "job": 104790967371,
      "time": 337,
      "config": "windows-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "10445782914"
    },
    {
      "job": 104790967257,
      "time": 148,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "10445184015"
    },
    {
      "job": 104790967434,
      "time": 122,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "10445129031"
    },
    {
      "job": 104790967245,
      "time": 383,
      "config": "windows-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10445783031"
    },
    {
      "job": 104790967351,
      "time": 102,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10446340294"
    }
  ],
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897",
  "_status": "success",
  "_upstream": "https://github.com/cran/IntegMultiReg",
  "_commit": {
    "id": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
    "author": "Thierry Chekouo <tchekouo@umn.edu>",
    "committer": "cran-robot <csardi.gabor+cran@gmail.com>",
    "message": "version 0.1.3\n",
    "time": 1789559386
  },
  "_maintainer": {
    "name": "Thierry Chekouo",
    "email": "tchekouo@umn.edu",
    "login": "chekouo",
    "description": "",
    "uuid": 42840133,
    "orcid": "0000-0002-3594-9182"
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 4.0.0",
      "role": "Depends"
    },
    {
      "package": "graphics",
      "role": "Imports"
    },
    {
      "package": "grDevices",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "utils",
      "role": "Imports"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    },
    {
      "package": "testthat",
      "version": ">= 3.0.0",
      "role": "Suggests"
    }
  ],
  "_owner": "cran",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2026-32",
      "n": 1
    },
    {
      "week": "2026-34",
      "n": 1
    },
    {
      "week": "2026-38",
      "n": 1
    }
  ],
  "_tags": [
    {
      "name": "0.1.0",
      "date": "2026-08-09"
    },
    {
      "name": "0.1.1",
      "date": "2026-08-22"
    },
    {
      "name": "0.1.3",
      "date": "2026-09-16"
    }
  ],
  "_stars": 0,
  "_contributors": [
    {
      "user": "chekouo",
      "count": 3,
      "uuid": 42840133
    }
  ],
  "_userbio": {
    "uuid": 42840133,
    "type": "user",
    "name": "Thierry Chekouo",
    "followers": 2
  },
  "_downloads": {
    "count": 228,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/IntegMultiReg"
  },
  "_searchresults": 4,
  "_topics": [
    "gsl"
  ],
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/IntegMultiReg.html",
    "extra/manual.pdf",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/readme.html",
    "extra/readme.md"
  ],
  "_realowner": "chekouo",
  "_cranurl": false,
  "_releases": [
    {
      "version": "0.1.0",
      "date": "2026-08-09"
    },
    {
      "version": "0.1.1",
      "date": "2026-08-22"
    }
  ],
  "_exports": [
    "coef_imr",
    "compare_imr",
    "cv_imr",
    "imr",
    "imr_data",
    "plot_imr",
    "plot_subgroup_sizes",
    "plot_top_features",
    "posterior_draws",
    "posterior_summary",
    "predict_imr",
    "summary_imr",
    "validate_imr",
    "validate_imr_data"
  ],
  "_datasets": [
    {
      "name": "kircIMR",
      "title": "Reduced TCGA-KIRC Multi-Platform Survival Example",
      "object": "kircIMR",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "simIMR",
      "title": "Simulated Multi-Platform Example Data",
      "object": "simIMR",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "as.data.frame.imr_data",
      "title": "Convert IMR Data to an Availability Data Frame",
      "topics": [
        "as.data.frame.imr_data"
      ]
    },
    {
      "page": "coef.imr",
      "title": "Marginal Posterior Inclusion Probabilities of an IMR Fit",
      "topics": [
        "coef.imr",
        "coef_imr"
      ]
    },
    {
      "page": "compare_imr",
      "title": "Compare Fitted IMR Models",
      "topics": [
        "compare_imr"
      ]
    },
    {
      "page": "confint.imr",
      "title": "Credible Intervals for an IMR Fit",
      "topics": [
        "confint.imr"
      ]
    },
    {
      "page": "cv_imr",
      "title": "Cross-Validated Predictive Accuracy of an IMR Fit",
      "topics": [
        "cv_imr"
      ]
    },
    {
      "page": "imr",
      "title": "Fit the Integrative Bayesian Multi-Platform Regression Model",
      "topics": [
        "imr",
        "imr.default",
        "imr.formula",
        "imr.imr_data"
      ]
    },
    {
      "page": "imr_data",
      "title": "Validated Multi-Platform Data for IMR",
      "topics": [
        "imr_data"
      ]
    },
    {
      "page": "imr_posterior_methods",
      "title": "Summarize Regression Posterior Draws",
      "topics": [
        "coef.imr_posterior",
        "confint.imr_posterior",
        "imr_posterior_methods",
        "print.imr_posterior",
        "summary.imr_posterior"
      ]
    },
    {
      "page": "kircIMR",
      "title": "Reduced TCGA-KIRC Multi-Platform Survival Example",
      "topics": [
        "kircIMR"
      ]
    },
    {
      "page": "plot_subgroup_sizes",
      "title": "Plot the Availability Subgroup Sizes of an IMR Fit",
      "topics": [
        "plot_subgroup_sizes"
      ]
    },
    {
      "page": "plot_top_features",
      "title": "Plot the Top Selected Features of an IMR Fit",
      "topics": [
        "plot_top_features"
      ]
    },
    {
      "page": "plot.imr",
      "title": "Plot Method for IMR Fits",
      "topics": [
        "plot.imr",
        "plot_imr"
      ]
    },
    {
      "page": "posterior_draws",
      "title": "Sample Regression Coefficients and Residual Variances",
      "topics": [
        "posterior_draws"
      ]
    },
    {
      "page": "posterior_summary",
      "title": "Posterior Uncertainty Summary for an IMR Fit",
      "topics": [
        "posterior_summary",
        "posterior_summary.imr"
      ]
    },
    {
      "page": "predict.imr",
      "title": "Predict Outcomes for New Subjects",
      "topics": [
        "predict.imr",
        "predict_imr"
      ]
    },
    {
      "page": "predict.imr_posterior",
      "title": "Predict Using Coefficient Posterior Draws",
      "topics": [
        "predict.imr_posterior"
      ]
    },
    {
      "page": "print.imr",
      "title": "Print Method for IMR Fits",
      "topics": [
        "print.imr"
      ]
    },
    {
      "page": "simIMR",
      "title": "Simulated Multi-Platform Example Data",
      "topics": [
        "simIMR"
      ]
    },
    {
      "page": "summary.imr",
      "title": "Summarize an IMR Fit",
      "topics": [
        "print.summary.imr",
        "summary.imr",
        "summary_imr"
      ]
    },
    {
      "page": "validate_imr",
      "title": "Validate a Fitted IMR Model",
      "topics": [
        "validate_imr"
      ]
    },
    {
      "page": "validate_imr_data",
      "title": "Validate an IMR Data Object",
      "topics": [
        "validate_imr_data"
      ]
    }
  ],
  "_readme": "https://github.com/cran/IntegMultiReg/raw/HEAD/README.md",
  "_rundeps": [],
  "_sysdeps": [
    {
      "shlib": "libgsl",
      "package": "libgsl28",
      "headers": "libgsl-dev",
      "source": "gsl",
      "version": "2.8+dfsg-6",
      "name": "gsl",
      "homepage": "https://www.gnu.org/software/gsl",
      "description": "GNU Scientific Library (GSL) -- library package"
    }
  ],
  "_vignettes": [
    {
      "source": "IntegMultiReg.Rmd",
      "filename": "IntegMultiReg.html",
      "title": "Integrative Bayesian Multi-Platform Regression with IntegMultiReg",
      "author": "Sinian Zhang, Thierry Chekouo",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Overview",
        "Real TCGA-KIRC example",
        "Fitting the model",
        "Inspecting selected biomarkers",
        "Predicting new subjects",
        "Assessing predictive performance",
        "Other outcome types",
        "References"
      ],
      "created": "2026-08-09 08:20:07",
      "modified": "2026-08-09 08:20:07",
      "commits": 1
    }
  ],
  "_score": 3.1760912590556813,
  "_indexed": true,
  "_nocasepkg": "integmultireg",
  "_universes": [
    "chekouo"
  ],
  "_previous": "0.1.1",
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.1.3",
      "date": "2026-09-16T12:22:52.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/9e49f91915a1d541b997940256c729747176ce80a97a1142298419e5788d3e71",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.1.3",
      "date": "2026-09-16T12:23:22.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/63b16c7baf838cf14323b3828b694dd06f4194243e8a1bac6a0b22712f71c366",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "0.1.3",
      "date": "2026-09-16T12:22:30.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/5a04d4002635bc44a2112f6c5791614517f7de8bc15251ffaad7b43f71696de0",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "0.1.3",
      "date": "2026-09-16T12:22:20.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/c6de728bed3032eef627e80e924191954e9642b1020a72a2cee7546fe389ae12",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.1.3",
      "date": "2026-09-16T12:25:50.000Z",
      "arch": "aarch64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/cc4fa6bb1a7305558e9c1fc37021712c6a4d14a5e84c32e288f551cf6357dece",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.1.3",
      "date": "2026-09-16T12:26:20.000Z",
      "arch": "x86_64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/c33aa6d48915de1028da4899de8c33731b8131a93f4b62f0063d828306b3d024",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "0.1.3",
      "date": "2026-09-16T12:25:28.000Z",
      "arch": "aarch64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/eee8a2f0b23b66687cb87bc6f037cf36a7ce35295e294cac4763063f532b733e",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "0.1.3",
      "date": "2026-09-16T12:27:12.000Z",
      "arch": "x86_64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/6d7cf780ea10a89cc52a9bc1f3e49aee239a459f5e1b7379670156d8d05a1b4d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "0.1.3",
      "date": "2026-09-16T12:22:29.000Z",
      "arch": "emscripten",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/580b88d52db911cdde5820e5bd4e48511b8d5877ac936c8386b57414bd3a94d1",
      "status": "success",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "0.1.3",
      "date": "2026-09-16T12:25:04.000Z",
      "arch": "aarch64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/444960bdd1e6a16eb4274beee842f8bcc8770464a6d78d35d1ccdbb332eaf8ae",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "0.1.3",
      "date": "2026-09-16T12:21:40.000Z",
      "arch": "x86_64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/6ca6d305da7f1dcecfc071693e1d9fe11ad5d2ed5dc6bf89115a9479d4820195",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "0.1.3",
      "date": "2026-09-16T12:21:48.000Z",
      "arch": "x86_64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/1e666314d10040580540cf93204c0ae4997d6685db1b20f56d2917264f814a8c",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "0.1.3",
      "date": "2026-09-16T12:25:59.000Z",
      "arch": "aarch64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/3c1690305923fd15525cb6ee36d8e701a6c470e6f16a40f86edc4ad99b614ef0",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "0.1.3",
      "date": "2026-09-16T12:21:31.000Z",
      "arch": "x86_64",
      "commit": "94377eb6b938b445ffb9b7d9352f3ea1e8adc025",
      "fileid": "https://r2.ropensci.org/6bb60dff26beff1864252ec394a6d7334615549195a5d5a4e815ec7f29db29f2",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/chekouo/actions/runs/35094896897"
    }
  ]
}